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Begum, Firdushi
- Study of Vitamin-D Status in Patients with Low Backache
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Authors
Affiliations
1 Department of Neurology, Gauhati Medical College & Hospital, Guwahati, Assam, IN
2 Department of Biochemistry, Gauhati Medical College & Hospital, Guwahati, Assam, IN
3 Department of Anesthesiology, Gauhati Medical College & Hospital, Guwahati, Assam, IN
1 Department of Neurology, Gauhati Medical College & Hospital, Guwahati, Assam, IN
2 Department of Biochemistry, Gauhati Medical College & Hospital, Guwahati, Assam, IN
3 Department of Anesthesiology, Gauhati Medical College & Hospital, Guwahati, Assam, IN
Source
International Journal of Health Research and Medico Legal Practice, Vol 3, No 1 (2017), Pagination: 81-84Abstract
Introduction: Apart from its established role in calcium homeostasis, studies have found vitamin D to be very much important for the normal maintenance and functioning of the muscles and nerves. Aims: i) To study the vitamin D levels in patients of low back ache ii) compare it with a control population. Methods: The study was designed as a case control study, with 100 cases and 100 controls. Patients with complaint of low backache were included in the study. A sample of venous blood was collected for vitamin D estimation. Results: In this study mean vitamin D level in the case group was found to be 29.19 ng/ml and in the control group 38.45ng/ml. P-value was found to be <.0001. Vitamin D deficiency and insufficiency was found more in females than males in both groups. 77.5% of the female patients and 45% of male patients had below normal vitamin D levels. Conclusion: There is a high possibility that vitamin D deficiency has a role to play in the aetiology of low backache.Keywords
Hypovitaminosis D, Myopathy, Pro-Inflammatory, Skeletal, Supplementation.References
- Dionne CE, Dunn KM, Croft PR, Nachemson AL, Buchbinder R, Walker BF, et al. A consensus approach towards the standardization of back pain definitions for use in prevalence studies. Spine 2008;33:95-103.
- Wadell G, Burton AK. Occupational health guidelines for the management of low back pain at work: evidence review. Occupational Medicine 2000;51(2):124-35.
- Deyo RA. Diagnostic evaluation of LBP-reaching a specific diagnosis is often impossible. Arch Intern Med 2002;162:1444-7.
- Ali JMM. Vitamin D deficiency in outpatient department: eastern province of KSA experience. Rawal Med J 2010;35:221-3.
- Schleithoff SS, Zittermann A, Tenderich G et al. Vitamin D supplementation improves cytokine profiles in patients with congestive heart failure: a double-blind randomized, placebocontrolled trial. Am J Clin Nutr 2006;83:754-9.
- D’Ambrosio D, Cippitelli M, Cocciolo MG, Mazzeo D, Di Lucia P, Lang R et al. Inhibition of IL-12 production by 1,25-dihydroxyvitamin D3. Involvement of NF-kappa B down regulation in transcriptional repression of the p40 gene J Clin Invest 1998;101:252-62.
- Holick MF, Chen TC. Vitamin D deficiency: a worldwide problem with health consequences. Am J Clin Nutr 2008;87:1080S-6S.
- Arabi A, El Rassi R, El-Hajj Fuleihan G. Hypovitaminosis D in developing countries-prevalence, risk factors and outcomes. Nat Rev Endocrinol 2010;6:550-61.
- Van der Meer IM, Middelkoop BJ, Boeke AJ, Lips P. Prevalence of vitamin D deficiency among Turkish, Moroccan, Indian and subSahara African populations in Europe and their countries of origin: An overview. Osteoporos. Int 2011;22:1009–21.
- Harinarayan CV, Joshi SR. Vitamin D status in India-Its implications and Remedial Measures. J Assoc Physicians India 2009;57:40-8.
- Zargar AH, Ahmad S, Masoodi SR, Wani AI, Bashir MI, Laway BA et al. Vitamin D status in apparently healthy adults in Kashmir valley of Indian subcontinent. Postgrad Med J 2007;83(985):713-6.
- Plotnikoff GA, Quigley JM. Prevalence of severe hypovitaminosis D in patients with persistent, nonspecific musculoskeletal pain. Mayo Clin Proc 2003;78(12):1463-70.
- McCarty DE, Reddy A, Keigley Q, Kim PY, Cohen S, Marino AA. Nonspecific pain is a marker for hypovitaminosis D in patients undergoing evaluation for sleep disorders: a pilot study. Nat Sci Sleep 2013;5:37-42.
- Al Faraj S, Al Mutairi K. Vitamin D deficiency and chronic low back pain in Saudi Arabia. Spine (Phila Pa 1976) 2003;28(2):177-9.
- Rao Ch R, Maruthi W. Study of Beneficial Role of Vitamin D in Chronic Low Back Pain. Paripex-Indian J of Research 2015;4(7):68-70.
- Holick MF, Binkley NC, Bischoff-Ferrari HA, Gordon CM, Hanley DA, Heaney RP et al. Evaluation, treatment, and prevention of vitamin D deficiency: an Endocrine Society clinical practice guideline. J Clin Endocrinol Metab 2011;96(7):1911-30.
- Atherton K, Berry DJ, Parsons T, Macfarlane GJ, Power C, Hypponen E. Vitamin D and chronic widespread pain in a white middle-aged British population: evidence from a cross-sectional population survey. Annals of the Rheumatic Diseases 2009;68(6):817–22.
- Benson J, Wilson A, Stocks N, Moulding N. Muscle pain as an indicator of vitamin D deficiency in an urban Australian Aboriginal population. Medical Journal of Australia 2006;185(2):76–7.
- Lotfi A, Abdel-Nasser AM, Hamdy A, Omran AA, El-Rehany MA. Hypovitaminosis D in female patients with chronic low back pain. Clinical Rheumatology 2007;26(11):1895–1901.
- Simonelli C. The role of vitamin D deficiency in osteoporosis and fractures. Minn Med 2005;88:34-6.
- Bischoff-Ferrari HA, Giovannucci E, Willett WC, Dietrich T, Dawson-Hughes B. Estimation of optimal serum concentrations of 25-hydroxyvitamin D for multiple health outcomes. Am J Clin Nutr 2006;84(1):18-28.
- Lodh M, Goswami B, Mahajan RD, Sen D, Jajodia N, Roy A. Assessment of vitamin D status in Patients of Chronic Low Back Pain of Unknown Etiology. Ind J Clin Biochem 2015;30(2):174-9.
- Ghai B, Bansal D, Kapil G, Kanukula R, Lavudiya S, Sachdeva N. High Prevalence of Hypovitaminosis D in Indian Chronic Low Back Patients. Pain Physician 2015;18:E853-E862.
- Kalra S, Kalra B, Khandelwal SK. Vitamin D status in patients with musculoskeletal symptoms in Haryana. Indian J Med Nutr Nutraceut. 2012;1:50-3.
- Plotnikoff GA, Quigley JM. Prevalence of severe hypovitaminosis D in patients with persistent, non-specific musculoskeletal pain. Mayo Clin Proc 2003;78:1463-70.
- Stoll D, Dudler J, Lamy O, Hans D, So A, Krieg MA et al. High prevalence of hypovitaminosis D in a Swiss rheumatology outpatient population. Swiss Med Wkly 2011;141:W13196.
- Lofti A, Abdel-Nasser AM, Hamdy A, Omran AA, El-Rehany MA. Hypovitaminosis D in female patients with chronic low back pain. Clin Rheumatol 2007;26:1895-1901.
- Jalili A, Bahrabadi M, Zare S. Prevalence of vitamin D deficiency in Nonspecific Musculoskeletal Pain . Shafa Orthopedic Journal 2015;2(4):e4052.
- Schreuder F, Bernsen R, van der Wouden JC. Vitamin D supplementation for non-specific musculoskeletal pain in non-western immigrants: a randomized controlled trial. Ann Fam Med 2012;10:547-55.
- Yetley EA. Assessing the vitamin D status of the US Population. The Am J of Clin Nutr 2008;88(2):558S-564S.
- Mitsikostas DD, Tsaklakidou D, Athanasiadis N, Thomas A. The prevalence of headache in Greece: correlations to latitude and climatological factors. Headache 1996;36(3):168-73.
- Zeng QY, Chen R, Xiao Y et al. Low prevalence of knee and back pain in southeast China; the Shantou COPCORD study. Journal of Rheumatology 2004;31(12):2439-43.
- Zhang Y, Leung DY, Richers BN, Liu Y, Remigio LK, Riches DW et al. Vitamin D inhibits monocyte/macrophage proinflammatory cytokine production by targeting MAPK phosphatase. J Immunol 2012;188(5):2127-35.
- Lacativa PGS, Farias ML. Osteoporosis and inflammation. Arq Bras Endocrinol Metab 2010;54(2):123-32.
- Bischoff-Ferrari HA, Dawson-Hughes B, Willett WC, Stachelin HB, Bazemore MG, Zee RY et al. Effect of vitamin D on falls: a metaanalysis. JAMA 2004;291:1999-2006.
- Kim TH, Lee BH, Lee HM, Lee SH, Park JO, Kim HS et al. Prevalence of Vitamin D deficiency in patients with lumbar spinal stenosis and its relationship with pain. Pain Physician 2013;16(2):165-76.